Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

The night's biggest winners may have been hosts Ms. Fey and Ms. Poehler, whose second time hosting the Hollywood Foreign Press Association's Beverly Hills, Calif., ceremony was just as successful as last year's show (a six-year ratings high with 19.7 million viewers).
译文属可可原创,仅供学习交流使用,未经许可请勿转载
我是说,让一个9号秀同伊巴卡和杰夫格林这样带队真的没问题吗?可能吧。只是从之前糟糕的表现上来看……
这是自从2001年来第一次由一名既不是小梅瑟威、也不是泰格·伍兹的运动员,荣登收入榜第一名。
['si:nj?]
这一点毋庸置疑。从卫生间标志到时装秀,性别界线正在加速变得模糊。现在我们差不多该抛弃传统的“女孩用粉色,男孩用蓝色”的成见了。
根据研究机构Millward Brown编制的BrandZ最新排行榜,全球100个最具价值品牌的品牌价值仍远远领先于其他品牌,今年它们的总价值上升3%,至3.4万亿美元。
去年,韩国教育部发布了一本手册就整形手术综合症对韩国高中生发出了警告,引用了迈克尔?杰克逊以及一个韩国女性因对整形上瘾导致脸部怪异浮肿的案例。
There was no indication of the identity of the kidnappers or their motive.
6. Miranda Kerr
You'd love to know the balance of forces that shape and move your ponytail, right? That's why Joseph Keller, Raymond Goldstein, Patrick Warren and Robin Ball received this igNOMINIOUS prize!
calculation
Few of the Fed's forecasts have proceeded according to plan over the course of the sharp economic downturn and choppy recovery, a fact that Fed officials now openly acknowledge. 'We have been disappointed in the pace of growth, and we don't fully understand why,' Fed Chairman Ben Bernanke said at his final news conference last month.
spontaneous
Not every band can sound fresh 40 years into a career, but not every band is Blondie.
17 November
《大空头》,导演:亚当·麦凯。
This summer, Noel will enter restricted free agency expecting to be compensated handsomely given his demonstrated defensive impact, untapped potential and lottery pick pedigree, even though he's logged fewer than 5,000 minutes during his career.
Entrepreneurs are movers and shakers. They can’t afford to analyze every detail or they’d never get anywhere. There is no place for procrastination in a startup. It’s a 24/7, no-vacation-or-sick-days kind of job that demands constant forward momentum. Make a brief assessment at every step and move on it. Trust your instincts.
In an emailed statement, FIFA said that during group stage matches, it sold a total of 143,364 of the cheapest tickets, which amounted to roughly 3,000 such tickets available per match.
通用汽车现在已经对挥泪大促销上瘾,新首席执行长惠塔克里(Ed Whitacre)对此心知肚明。他将在2010年取消一些购买刺激措施,以放弃全美20%市场占有率目标的方式来谋求重获盈利能力。这番求索注定是前路艰难。
如果2017年是假新闻之年,那么2018年将成为假数据之年。就像假新闻以多种不同形式出现一样——既有被美国总统称为假新闻的真新闻,也有在社交媒体上吸引众多观众的无稽之谈——假数据也是如此。
11月18日
3. Tablets meet viruses.
5. Life is like a coffee table: it’s got tea sets and dinnerware all over it. (beiju, 杯具, is a homophone for tragedy, 悲剧, and dinnerware, canju, 餐具, a homophone for disaster, 惨剧).


If a sitcom that lasts for 10 years is considered popular, then surely one that still stirs up emotions after 20 must be considered a classic. Friends first aired in the US in 1994, featuring a cast of six young men and women in New York. In the time since, it’s become one of the most famous titles in the sitcom genre, aired in over 100 countries and regions in the world.
自从18个月前在亚洲设立业务以来,克拉布一直没有涉足香港房地产市场,因为他表示,价格太高了,可担负性太差。
在甲骨文球场以77比111耻辱性地输掉的这场比赛中,科比11投仅1中,其中三分球7投1中,全场只拿下4分。在上个赛季输给圣安东尼奥马刺队的比赛中。他也曾14投1中。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

通过ETF购买计划,日本央行间接持有约22家日本大企业10%的股权,并持有整个日本股市的3%左右。一些人批评称,这是对日本股市“事实上的国有化”。
发布日期:2015年春季
['hedwei]
The US remains home to the biggest brands and the value of its top 10 increased by 10 per cent to $1.3tn in 2016. The top 10 UK brands, headed by Vodafone, lost 8 per cent of their value. Those in continental Europe — led by Germany’s SAP software group — rose 5 per cent. Finally, the $360bn value of Asia’s top 10 brands, headed by Tencent, China Mobile and Alibaba, was only 10 per cent lower than the value of the top 10 in continental Europe and the UK combined.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

他进一步补充到,“有大约70名法国公民为恐怖分子当兵战死在叙利亚和伊拉克。”

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Chinese Premier Li Keqiang delivers a government work report during the opening meeting of the fourth session of the 12th National People's Congress at the Great Hall of the People in Beijing, capital of China, Mar 5, 2016.
伦敦商学院课程的一个主要优势是学员来自地域广泛的不同国家。其2015年MBA课程学员的90%来自海外,来自大约60个不同国家。

约瑟夫?斯蒂格利茨(Joseph Stiglitz)等诺贝尔经济学奖得主、比尔?麦吉本(Bill McKibben)等环保活动人士、乔治?索罗斯(George Soros)及新经济思维研究所(Institute for New Economic Thinking)、阿尔?戈尔(Al Gore)和其他现代思想家全都提醒我们,传统经济学家(以及他们效力的银行、企业和政府机构)都已对坏的经济学理论成瘾,他们在破坏美国的未来。
《性别之战》
survival
这款智能产品的使用可以追溯到1800年,但在2016年它才变得“智能”。 Meet Peggy,这种洗衣挂钩能够“帮助你减轻负担”,它会在洗衣机洗好衣服的时候提醒你,并告诉你天气是否适宜晾晒衣服。该装置连接到您的手机,它会在天气变化或是需要转移晾衣服的地方时发消息提醒你。
We began the year worried that the US was poised to withdraw from the World Trade Organisation. That hasn’t happened. And it’s now unlikely to any time soon.
节目13 歌曲《嫦娥》,李玉刚 景海鹏 刘旺 刘洋

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


佛山陶瓷迁都清远 中国新瓷都熊熊窑火已经点燃


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


这一新数据公布之际,杜特尔特正抵御国内外对其禁毒运动的指责,已有60万名潜在嫌疑人向当局自首。
制造业表现较好,利润增长6.5%。受低廉的能源价格的提振,电力、热力、燃气及水生产和供应业利润增长17%。
One of the biggest trends I’m noticing in entrepreneurship right now focuses on access. Innovators are taking what was once costly, time-intensive, or otherwise beyond reach and efficiently offering it to consumers. Whether it’s learning new skills, inspiring a new interest, or tapping into formerly cost-prohibitive markets, entrepreneurs are finding new ways to bring the unique and specialized to a more mainstream market. We started to see this with collaborative consumption business models and I predict we’ll continue to see an influx of ‘access-based’ business models in the year ahead.
2012年有哪些品牌通过社交媒体提升了它们的声誉?哪些公司则越来越差了?
The parallels between Snapchat, the upstart "sexting" service, and social media behemoth Facebook (FB) in its early days are uncanny. We all know how well Zuckerberg's long bet paid off (not to mention how thoroughly he vanquished those dastardly Winklevoss twins). Could Snapchat's future be just as bright?
v. 抢劫,掠夺
2010年英文新年祝福邮件
IT/通信/电子/互联网行业的应届生签约最高月薪为4867元,同比去年下降826元;紧随其后的是金融业和交通/运输/物流/仓储行业,平均签约月薪分别是4692元和4457元。
但是更让人兴奋的是,魔术师约翰逊是一个人脉广泛且备受尊敬的名人堂球员,他看起来也能知人善任,新经理罗布-佩林卡是一个老谋深算的交易者,他在联盟人脉也很广。
Most female participants were between 19 and 23.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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n. 谷物,小麦,玉米
该新规还专门针对出租车服务作出规定。
Industrial production expanded 1.4 per cent month-on-month in October, the quickest pace since a 4.1 per cent rise in January. It was better than the 1.1 per cent gain in September, but still fell short of economists' expectations for a gain of 1.8 per cent.
审校:赵倩 来源:前十网

DIHK's foreign business chief Volker Treier said the volume of goods exported to China from Germany grew rapidly in the latter part of 2016, Chinanews.com reported.

  • Only the first three authors are listed, followed by "et al."
  • 龙江拟打造亚洲最大家具材料电商平台
  • 大兴机场真机试飞定在下周一


When many millennials struggle to find jobs or make do in low-skilled positions, these masters programmes achieve strong employment rates thanks to their links with corporate partners and alumni networks.
If any movie can bridge the deep racial, generational and class divides in American life — at least for a couple of hours — it would have to be this revival of the ancient “Rocky” franchise. Sylvester Stallone, shuffling into the wise old trainer role, gives perhaps the loosest, warmest performance of his career. Michael B. Jordan, as Adonis Johnson, Rocky’s protégé (and the illegitimate son of his onetime rival and long-lost friend, Apollo Creed), continues his emergence as one of the vital movie stars of our moment. As for Mr. Coogler, with his second feature as a director he proves himself to be a true contender. (Read the review)

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